(Nerium indicum)
“Pet poisonous” – Toxic parts: leaves Nerium indicum is an oleander plant species . Nerium indicum is included in the genus oleanders , and the family oleander plants . In addition to the nominate form, there is also the subspecies N. i. Indicum . Oleander has historically been considered a poisonous plant because some of its compounds may exhibit toxicity, especially to animals, when consumed in large amounts. Among these compounds are oleandrin and oleandrigenin, known as cardiac glycosides, which are known to have a narrow therapeutic index and can be toxic when ingested. Toxicity studies of animals administered oleander extract concluded that rodents and birds were observed to be relatively insensitive to oleander cardiac glycosides. Other mammals, however, such as dogs and humans, are relatively sensitive to the effects of cardiac glycosides and the clinical manifestations of "glycoside intoxication".